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Skin aging
During aging, fundamental changes occur in the skin associated with the main cell population of the dermis - fibroblasts: their numbers and biosynthetic activity decrease, the balance between the processes of synthesis and degradation of the intercellular matrix of the dermis is disrupted.
Studies have shown that in older people, compared to younger people, the total number of fibroblasts in the skin is on average lower 35 %.
Collagen production in the skin of older people is reduced by an average of 75%, which is also associated with fibroblast activity.
As a result, the natural consequence of these processes is a decrease in skin thickness, a decrease in its elasticity and firmness, and the formation of wrinkles.
Technology algorithm
- Taking a biopsy from the behind-the-ear space (15 min)
- Obtaining a primary culture of skin fibroblast cells (1 month)
- Cultivation of cell culture in the laboratory up to 100 million cells (1 month)
- Evaluation of proliferative activity. Skin certification. (parallel to stage #3)
- Intradermal cell injection procedure (60 min)
- Preservation of cellular biomaterial in cryostorage (1 year – ∞)
- Exсlusively by IBC: production of autologous exosomes.
- The second stage of therapy is the use of exosomes at home
(for 6 months after the procedure)
Application areas
- Cosmetology;
- Dermatology;
- Correction of scars and marks;
- Anti-age therapy and rejuvenation.
Exclusive IBC technology
Skin Eternity – exclusive IBC technology for the preservation and use of the skin’s own (autologous) cells – fibroblasts.
It is a personalized complex of diagnostic and therapeutic procedures for restoration, rejuvenation and improvement of the quality and health of the skin at the cellular level.
The procedure provides a long-lasting natural rejuvenating effect by correcting the causes of skin aging, and not just their consequences.
The procedure eliminates the development of allergic reactions and other side effects, since only the patient’s own skin cells are used.
Clinical result:
The clinical effect is gradually increasing and long-term, since the skin’s own functionally active cells are used.
The procedure eliminates the development of allergic reactions and other side effects, since only the patient’s own skin cells are used.
Patients begin to notice an improvement in the condition of the skin (increased elasticity and thickness, reduced number and depth of wrinkles, improved color) within 10-14 days after the procedure.
Uniqueness:
Skin Eternity is the only method that allows you to combat not only the external manifestations of skin aging, but also the causes of aging at the level of its microstructure.
Technology allows replenish fibroblast deficiency that develops in the skin with age, due to the introduction into the skin of millions of young and active fibroblasts, which, after introduction into the skin, secrete cytokines and trigger a cascade of reactions that initiate the synthesis of all necessary substances by the skin's own cells.
All other cosmetic methods only stimulate the work of fibroblasts present in the skin, the number of which significantly decreases with age.
- Primary isolation of autologous fibroblasts, diagnostic determination of cell proliferative activity (Skin Passport), creation of a bank of skin's own fibroblasts, production of cellular material for the production of Skin Eternity preparation
- Obtaining and producing exosomal vesicles (exosomes) obtained from autologous dermal fibroblasts obtained in the first stage
- Cultivation of cell culture of autologous dermal fibroblasts up to 100x10^6 million.
- Storage of cellular biomaterial in liquid nitrogen in a cryobank